Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Boston Scientific receives CE Mark for Lotus™ Valve System

Boston Scientific Corporation (NYSE: BSX) has received CE Mark for the Lotus™ Valve System, the company's advanced transcatheter aortic valve replacement (TAVR) technology.  This key approval offers a unique and effective new treatment alternative for patients with severe aortic stenosis at high risk with surgical valve replacement.

October 29, 2013

Heart cells keep a youthful profile

NBC News reported on a study in Genome Biology in which researchers studied aging of cells. The scientists proposed that some cells age more slowly than others, with cardiac cells clocking in as relative youngsters and tumor cells being the oldest of all. 

October 23, 2013

Cleveland Clinic names top 10 medical innovations for 2014

Cleveland Clinic today announced its eighth annual list of Top 10 Medical Innovations that will have a major impact on improving patient care within the next year. The list includes a bionic eye, a neurostimulator for epilepsy and fecal transplantation.

October 17, 2013

Medicure announces approval of recommended dosing regimen for Aggrastat

Medicure Inc. ("Medicure" or the "Company") (TSXV:MPH, OTC:MCUJF.PK), is pleased to announce that the United States Food and Drug Administration (FDA) has approved the AGGRASTAT (tirofiban HCl) high-dose bolus (HDB) regimen, as requested under Medicure's supplemental New Drug Application (sNDA). The AGGRASTAT HDB regimen (25 mcg/kg over 3 minutes, followed by 0.15 mcg/kg/min) now becomes the recommended dosing for the reduction of thrombotic cardiovascular events in patients with non-ST elevated acute coronary syndrome (NSTE-ACS).

October 16, 2013

Shutdown imperils studies’ progress

The New York Times reports that the government shutdown has crippled clinical trial activity at the National Institutes of Health. Only 12 patients have been enrolled since Oct. 1. Normally enrollment averages 200 new patients a week.

October 10, 2013

Atherotech presents latest evidence showing how comprehensive lipid testing can help improve cardiovascular disease outcomes

New research reveals the advantages of new, more accurate risk assessment methodologies over the basic lipid panel. Atherotech Diagnostics Lab, a leading clinical reference laboratory specializing in advanced cardiometabolic testing and disease management solutions, will highlight recent evidence for improved cardiovascular disease assessment and prevention at the eighth annual Cardiometabolic Health Congress (CMHC) October 2-5, at the Sheraton Hotel in Boston.    

October 1, 2013

Ohio State's heart program names 2013 Schottenstein Laureate

The Ohio State University Wexner Medical Center's Heart and Vascular Center has named Dr. Garret FitzGerald, professor of Medicine and Pharmacology; chair of the Department of Pharmacology and director of the Institute for Translational Medicine and Therapeutics at the Perelman School of Medicine at University of Pennsylvania, the recipient of the 2013 Jay and Jeanie Schottenstein Prize in Cardiovascular Sciences.

September 26, 2013

Study comparing stroke therapies receives $2 million national research grant

An American Heart Association/American Stroke Association sponsored study comparing which stroke therapies work best has received a $2 million research award from the Patient-Centered Outcomes Research Institute (PCORI).

September 26, 2013

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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