Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Prominent cardiac cell biologist Jennifer Van Eyk, PhD, joins Cedars-Sinai to direct new advanced clinical biosystems research institute

Prominent proteomic and cardiac scientist Jennifer Van Eyk, PhD, has been named the inaugural director of Cedars-Sinai's Advanced Clinical Biosystems Research Institute.

March 21, 2014

Edwards Lifesciences announces first human implants with mitral transcatheter valve system

Edwards Lifesciences Corporation (NYSE: EW), the global leader in the science of heart valves and hemodynamic monitoring, today announced the successful completion of the first three human implants of its FORTIS mitral transcatheter heart valve, which were performed in February and March by the Heart Team at St. Thomas' Hospital in London.

March 8, 2014

The Montreal Heart Institute will pilot ARTERIA: a major research program for patients with or at risk of cardiovascular diseases

In the presence of Quebec Premier, Pauline Marois, ministers Nicolas Marceau, Jean-François Lisée and Élaine Zakaïb, Montreal Mayor, Denis Coderre, and the representatives of international pharmaceutical companies, Dr. Jean-Claude Tardif, Director of the Research Centre of the Montreal Heart Institute (MHI), announced today the launch of ARTERIA, a research program aimed at developing ground-breaking treatments for cardiovascular diseases, the number one cause of death worldwide.

February 27, 2014

'I am CardioSmart' contest recognizes coronary artery disease patient

Brenda Keene had a history of heart disease in her family, but she still didn't anticipate all the health problems she would face. After battling first breast cancer and then coronary artery disease beginning in her late 20s, she has made it her mission to fight for her health and encourage others to do the same.

February 27, 2014

Compound improves cardiac function in mice with genetic heart defect, MU study finds

Congenital heart disease is the most common form of birth defect, affecting one out of every 125 babies, according to the National Institutes of Health. Researchers from the University of Missouri recently found success using a drug to treat laboratory mice with one form of congenital heart disease, hypertrophic cardiomyopathy - a weakening of the heart caused by abnormally thick muscle. By suppressing a faulty protein, the researchers reduced the thickness of the mice's heart muscles and improved their cardiac functioning.

February 22, 2014

American Heart Association awards Loyola $438,740 for cardiac research

The American Heart Association has awarded Loyola University Chicago Stritch School of Medicine $438,740 for cardiac research in 2013, bringing the lifetime total the organization has awarded to Loyola to $10.6 million.

February 22, 2014

UTHealth, Memorial Hermann perform state’s first conscious sedation TAVR procedure

A team of interventional cardiologists and cardiovascular surgeons at The University of Texas Health Science Center at Houston (UTHealth) and Memorial Hermann Heart & Vascular Institute-Texas Medical Center performed Texas’ first transcatheter aortic valve replacement (TAVR) under conscious sedation using the Edwards Sapien valve.

February 17, 2014

Aegerion Pharmaceuticals' JUXTAPID (lomitapide) capsules approved in Canada for the treatment of homozygous familial hypercholesterolemia (HoFH)

Aegerion Pharmaceuticals, Inc. (Nasdaq:AEGR), a biopharmaceutical company dedicated to the development and commercialization of innovative therapies for patients with debilitating rare diseases, today announced that Health Canada has granted a Notice of Compliance (NOC) approving JUXTAPID as an adjunct to a low-fat diet and other lipid-lowering drugs, with or without LDL apheresis, to reduce low-density lipoprotein cholesterol (LDL-C) in adult patients with homozygous familial hypercholesterolemia (HoFH).

February 11, 2014

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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