Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Confirmed: AFib ablation more beneficial for patients with HFrEF than those with HFpEF
Researchers explored data from nearly 2,500 AFib ablation patients, sharing their findings in JAMA Cardiology.
Statin therapy may help HFpEF patients lower their risk of death, heart attack or stroke
All participants were free of ASCVD and had no history of statin use at the start of the study.
Diabetic cardiomyopathy treatment shows promise in ARISE-HF
James Januzzi Jr., MD, said the treatment's overall impact was neutral, but he and his team saw "a very clear and encouraging signal."
Keto diet ‘does not fulfill the criteria of a healthy diet,’ could be harmful for heart patients
The popular high-fat, low-carb diet is associated with multiple short-term benefits, but they appear to diminish over time.
Bayer subsidiary granted FDA’s fast track designation for new congestive heart failure treatment
AskBio, acquired by Bayer for more than $2 billion in 2020, is enrolling patients for a new clinical trial focused on the therapy's effectiveness in adult patients with non-ischemic cardiomyopathy and heart failure.

artificial intelligence AI deep learning

AI model uses DNA to predict AFib, heart failure

Scientists were able to identify a total of 21 genes linked to cardiovascular conditions such as AFib and heart failure.

March 1, 2023

ElectroDucer Sleeve PCI TAVR EuroIntervention

New direct wire pacing device shows potential during PCI and TAVR, first-in-human study finds

Early evidence suggests the Electroducer Sleeve is safe and effective among patients presenting for certain interventional procedures.

February 27, 2023

Tim Attebery, DSc, MBA, the CEO of Cardiovascular Associates of America and former CEO of the American College of Cardiology (ACC)

Q&A: Tim Attebery on why private equity-backed management companies are investing in cardiology

The CEO of Cardiovascular Associates of America, and former CEO of the American College of Cardiology, shared his perspective on the rise of private equity investments in cardiology.

February 22, 2023

Bertram Pitt, MD, a professor of medicine emeritus at the University of Michigan School of Medicine, explains the role of sodium–glucose co-transporter-2 (SGLT-2) inhibitors for heart failure (HF). Initially developed to treat diabetes, these drugs have been shown to improve HF outcomes in HF in several large, randomized trials over the past few years, including SOLOIST-WHF, DAPA-HF, EMPEROR-Preserved, and the DELIVER trials. The positive results earned their inclusion in the 2022 AHA/ACC/HFSA Guideline for

What clinical research tells us about sotagliflozin and heart failure

Some SGLT2 inhibitors have been linked to significant improvements in HF outcomes, but what about sotagliflozin? We spoke with Bertram Pitt, MD, to learn more.

February 21, 2023

Vericiguat consistently linked to positive outcomes, limited side effects among heart failure patients

Reviewing data from several studies, researchers wrote that vericiguat (Verquvo) could potentially "become a breakthrough in the treatment of heart failure."

February 16, 2023

Hackensack Meridian Health, New Jersey’s largest health network, recently announced it has signed a definitive agreement with Complete Care to acquire a majority of its long-term care facilities.

High-risk patients ineligible for bypass surgery see ‘profound improvements’ after PCI

High-risk patients with complex CAD who are ineligible for CABG can still see substantial benefits from PCI.

February 13, 2023

Tablet projecting metaphorical medical hologram

New guideline on mechanical circulatory support tackles device selection, ethical dilemmas and more

The Heart Failure Society of America and International Society for Heart and Lung Transplantation worked together on the document, hoping their recommendations serve as a "critical roadmap" for clinicians.

February 8, 2023

More than a feeling? Social isolation, loneliness linked to a higher heart failure risk

A new study published in JACC: Heart Failure offers more evidence that a patient's feelings can strongly influence their risk of poor cardiovascular health.

February 2, 2023

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Heart Failure

Confirmed: AFib ablation more beneficial for patients with HFrEF than those with HFpEF

Statin therapy may help HFpEF patients lower their risk of death, heart attack or stroke

Diabetic cardiomyopathy treatment shows promise in ARISE-HF

Keto diet ‘does not fulfill the criteria of a healthy diet,’ could be harmful for heart patients

Bayer subsidiary granted FDA’s fast track designation for new congestive heart failure treatment

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