Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Statin therapy may help HFpEF patients lower their risk of death, heart attack or stroke
All participants were free of ASCVD and had no history of statin use at the start of the study.
Diabetic cardiomyopathy treatment shows promise in ARISE-HF
James Januzzi Jr., MD, said the treatment's overall impact was neutral, but he and his team saw "a very clear and encouraging signal."
Keto diet ‘does not fulfill the criteria of a healthy diet,’ could be harmful for heart patients
The popular high-fat, low-carb diet is associated with multiple short-term benefits, but they appear to diminish over time.
Bayer subsidiary granted FDA’s fast track designation for new congestive heart failure treatment
AskBio, acquired by Bayer for more than $2 billion in 2020, is enrolling patients for a new clinical trial focused on the therapy's effectiveness in adult patients with non-ischemic cardiomyopathy and heart failure.
2 out of 5 AFib patients develop heart failure later in life
Stroke is typically seen as the biggest danger for patients after they receive an AFib diagnosis. This study, however, suggests heart failure could be an even bigger threat.

Medtronic stops sales and distribution of HVAD system due to multiple issues, including 14 patient deaths

The device's internal pump was associated with a heightened risk of adverse outcomes, including stroke and death.

June 3, 2021

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19% of heart attack survivors develop heart failure within 5 years

Patients with chronic kidney disease face an especially high risk of developing new-onset heart failure after discharge.

May 28, 2021

Landmark discovery provides clinicians with a ‘valuable clinical tool’ for diagnosing myocarditis

Researchers believe they have found the first blood biomarker for diagnosing myocarditis, sharing their findings in the New England Journal of Medicine.

May 27, 2021

Dapagliflozin a cost-effective treatment for HFrEF at its current price point

Researchers found that the SGLT2 inhibitor had similar value among patients with and without diabetes, sharing their findings in JAMA Cardiology.

May 27, 2021

The greatest benefit: Omecamtiv mecarbil improves outcomes the most for patients with severe heart failure

Researchers explored data from the GALACTIC-HF trial to evaluate how the severity of a patient's reduced ejection fraction impacts the benefits of omecamtiv mecarbil.

May 17, 2021

High blood pressure linked to greater risk of heart failure, AFib, heart attack, stroke

The authors evaluated data from more than 2.1 million patients, sharing their findings in Circulation.

May 13, 2021

FDA announces new recall of instructions for Medtronic’s HVAD system after 1 death, 64 injuries

This Class I recall covers more than 130,000 different devices, according to the FDA.

May 13, 2021

Abbott launches new clinical trial focused on treating AFib, heart failure at the same time

The TAP-CHF trial is expected to enroll up to 100 AFib patients with a history of HFpEF.

May 6, 2021

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Heart Failure

Statin therapy may help HFpEF patients lower their risk of death, heart attack or stroke

Diabetic cardiomyopathy treatment shows promise in ARISE-HF

Keto diet ‘does not fulfill the criteria of a healthy diet,’ could be harmful for heart patients

Bayer subsidiary granted FDA’s fast track designation for new congestive heart failure treatment

2 out of 5 AFib patients develop heart failure later in life

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