Left Atrial Appendage Closure

The left atrial appendage (LAA) of the heart is a common location where clots form in atrial fibrillation (AFib) patients that then embolism and cause a stroke. Closing off the LAA either surgically, with a clip or via transcatheter LAA closure device, closes the opening to the LAA to prevent clots from forming or embolizing. The clots are the reason why AFib patients need to be on anticoagulants. LAA occlusion (LAAO) enables patients to stop taking anticoagulation drugs. LAAO has been a rapidly growing segment of structural heart procedures since the approval of the first device, the Watchman, in 2015. Procedures are performed by electrophysiologists, interventional cardiologist or cardiac surgeons.

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Interview with Rebecca T. Hahn, MD, Professor of Medicine at Columbia University Irving Medical Center, Chief Scientific Officer of the Echo Core Lab at the Cardiovascular Research Foundation and Director of Interventional Echocardiography at the Columbia Structural Heart and Valve Center. She discusses some of the trends of growing use of interventional echocardiographic guidance in transcatheter structural heart procedures, the growing number of tricuspid valve procedures, and use of 3D ICE.

VIDEO: Trends in structural heart procedural imaging - a discussion with Rebecca Hahn

Rebecca T. Hahn, MD, Director of Interventional Echocardiography at the Columbia Structural Heart and Valve Center, discusses some of the trends in the growing use of interventional echocardiographic guidance in transcatheter structural heart procedures.

September 9, 2022
Watchman FLX left atrial appendage closure (LAAC)

Boston Scientific gains a new FDA approval for Watchman FLX LAAC device

The company can now update its labeling instructions for the device to include a new 45-day dual anti-platelet therapy treatment option when treating non-valvular atrial fibrillation. 

September 7, 2022
Illustration of a left atrial appendage occlusion (LAAO) procedure using a Watchman device. Image courtesy of Johns Hopkins Medicine. #LAA #LAAO

Pre-procedure CT imaging benefits LAA occlusion in Henry Ford study

There is not agreement among the top structural heart experts if CT is required for left atrial appendage occlusion (LAAO), but a Henry Ford Hospital study shows it can improve outcomes.

August 5, 2022
View of an Amulet left atrial appendage (LAA) occluder on 4D intra-cardiac echo (ICE) from a GE NuVision ICE catheter. Since ICE is operated by the interventionalist, it can be used to reduce the number of people needed to perform an LAA occlusion procedure.  

New LAA occluder technology and the debate on echo vs. CT image guidance

At TVT 2022, there was debate whether CT imaging is needed for preplanning LAA procedures, and several new devices in development were discussed.

July 6, 2022
Two examples of new left atrial appendage occluders (LAAO), the Conformal omn left and the Laminar on the right. evi Nair, MD, FACC, FHRS, director of cardiac electrophysiology at St. Bernard's Healthcare, Jonesboro, Arkansas, explains some of the recent advances in transcatheter left atrial appendage (LAA) occlusion technology at the 2022 Transcatheter Valve Therapeutics (TVT) Structural Heart Summit. #TVT #TVT2020 #LAA #LAAO #EPeeps

VIDEO: Advances in left atrial appendage occlusion technology

Devi Nair, MD, director of cardiac electrophysiology at St. Bernard's Healthcare, Jonesboro, Arkansas, explains some of the recent advances in transcatheter left atrial appendage (LAA) occlusion technology at the 2022 Transcatheter Valve Therapeutics (TVT) Structural Heart Summit.

June 24, 2022
Large peridevice leaks after left atrial appendage occlusion (LAAO) are incredibly rare and not associated with a greater risk of adverse outcomes, according to new research published in JACC: Clinical Electrophysiology.[1] Smaller residual links are more common, however, and associated with a risk of thromboembolic and bleeding events.

What peridevice leaks after LAAO mean for patient health

The study's authors reviewed data from more than 50,000 patients, presenting their findings in JACC: Clinical Electrophysiology.

June 20, 2022
The Boston Scientific Watchman device is a transcatheter device implanted in the left atrial appendage (LAA) to seal it off so atrial fibrillation patients can got off of anticoagulant therapy.

Real-world Watchman patients experiencing fewer complications after LAAO than seen in clinical trials

The study's authors compared findings from the PROTECT-AF and PREVAIL clinical trials with data from the NCDR LAAO Registry, focusing on short-term and long-term outcomes. 

May 3, 2022
IVUS guidance during DES implantation boosts long-term outcomes in new study

Amulet vs. Watchman: LAA occluder devices compared in new head-to-head trial

The Amulet's implantation success rate and LAA closure rate were both higher than the first-generation Watchman device, researchers reported.

September 2, 2021
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