Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Social media sites growing in popularity for LVAD patients and caregivers

Since former Vice President Dick Cheney had a left ventricular assist device (LVAD) implanted in 2012, general interest in the devices have increased and social media sites have included more information on them.

August 5, 2015

Data shows the CardioMEMS HF System adds incremental benefit when combined with device therapy and is cost effective

St. Jude Medical, Inc., a global medical device company, today announced important new data presented during the Heart Rhythm Society's (HRS) 36th annual Scientific Session supporting improved outcomes and cost-effectiveness of the CardioMEMS™ HF System for the management of Class III heart failure patients.

May 15, 2015

FDA approves investigational study for new smaller SynCardia Total Artificial Heart

SynCardia Systems, Inc. has received FDA approval to conduct an Investigational Device Exemption (IDE) clinical study on the effective use of its 50cc SynCardia temporary Total Artificial Heart.

March 31, 2015

New CHAMPION data show significant improvement in survival rates for heart failure patients with reduced ejection fraction

St. Jude Medical, Inc., a global medical device company, today announced a new data analysis from the CHAMPION trial showing that heart failure (HF) patients with reduced ejection fraction on optimal doses of guideline directed medical therapy (GDMT) managed by pulmonary artery (PA) pressure monitoring with the CardioMEMS™ HF System had a 57 percent reduction in mortality and a 43 percent reduction in HF hospitalizations compared with patients on GDMT managed by the standard of care (SOC). These data show a strong improvement for patients managed by optimal GDMT and the CardioMEMS HF System in both mortality and hospitalizations over currently defined best practices.

March 17, 2015

Home is where the (artificial) heart is

The recipient of a total artificial heart implanted in August is home and “living a completely normal life now,” according to the French surgeon who invented the device. The patient exercises by “pedaling like crazy” on a stationary bike.

January 20, 2015

Temporary but increasingly durable

Patients awaiting heart transplants can continue on ventricular assist devices for longer periods now, thanks to smaller profile devices with improved functionality, the Boston Globe reports.

December 8, 2014

Cardioxyl HNO prodrugs show effectiveness in preclinical models following oral administration, improve hemodynamics in chronic diastolic dysfunction

Researchers testing Cardioxyl Pharmaceuticals, Inc. experimental HNO prodrugs presented data demonstrating that HNO improves cardiac function in animal models of diastolic heart failure, and separately that an orally administered HNO prodrug produces the same attractive hemodynamic improvements previously demonstrated with intravenous infusion.

November 21, 2014

Boston scientist awarded American Heart Association prize for translating bench research into identifiable markers of CVD risk

The American Heart Association awarded its 2014 Population Research Prize to Vasan R. Ramachandran, M.D., of Boston University School of Medicine, “for brilliantly seizing upon opportunities to translate cutting-edge bench science into an epidemiological context, thereby making fundamental contributions to identifying systemic markers for cardiovascular risk, both here and in developing countries.”

November 18, 2014

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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