Pascal transcatheter mitral repair device performs as well as MitraClip in late-breaking CLASP IID Trial 

The Pascal transcatheter mitral valve repair system. Similar to the latest version of the MitraClip, the Pascal can operate each leaflet independently to grasp the mitral valve leaflets. Results of the CLASP IID trial at #TCT2022.
The Pascal transcatheter mitral valve repair system. Similar to the latest version of the MitraClip, the Pascal can operate each leaflet independently to grasp the mitral valve leaflets.

Comparison between transcatheter edge-to-edge repair (TEER) devices found Pascal was non-inferior compared with MitraClip in the CLASP IID pivotal trial.

Ultrasound guidance for femoral access did not reduce bleeding or vascular complications in TCT late-breaker

Use of ultrasound to guide needles used for femoral vascular access for cath lab procedures can help reduce bleeding and vascular complications. But the Universal Trial at TCT 2022 showed no difference. Image courtesy of Sonosite
Use of ultrasound to guide needles used for femoral vascular access used in cath lab procedures is believed to help reduce bleeding and vascular complications. But the UNIVERSAL trial at TCT 2022 showed no difference. Image courtesy of Sonosite

The UNIVERSAL Trial, one of the largest multicenter randomized trials comparing ultrasound with fluoroscopic guidance vs. fluoroscopic guidance alone, found there was no reduction in major vascular access complications. 

Renal denervation lowered blood pressure in two late-breaking TCT trials 

Positive data was presented on the first-generation Symplicity (left) long-term outcomes and from the Recor ultrasound renal denervation system pivotal trial at TCT 2022. #TCT #TCT2022
Positive data was presented on the first-generation Symplicity (left) long-term outcomes data, and from the Recor ultrasound renal denervation system (right) pivotal trial at TCT 2022.

Results from the Medtronic SYMPLICITY HTN-3 trial long-term results and the pivotal RADIANCE II trial for the Recor ultrasound renal denervation system lowered blood pressure effectively in drug-resistant patients.