Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

cardiac amyloidosis on bone scan

Cardiac amyloidosis becoming less rare thanks to nuclear medicine studies

A new study in the Journal of Nuclear Medicine offers insight into how the condition affects the general population, as well as how radiologists can help in the cardiac amyloidosis diagnostic journey.

January 4, 2023
Barry L. Zaret, MD

Veteran cardiologist, viewed by many as the founder of nuclear cardiology, dies at 82

Barry L. Zaret, MD, was an influential cardiologist, accomplished poet and veteran of the United States Air Force. 

October 28, 2022
Comparison of flurpiridaz F-18 PET, SPECT and angiography of the 60-year-old female patients in the Aurora trial. The SPECT scan appeared normal, but flurpiridaz was shown to be more sensitive and showed the ischemia from two blockages in the right coronary artery. The new radiotracer may help expand cardiac PET. #ASNC

Flurpiridaz data shows promise to expand and enhance cardiac PET

The biggest news from the American Society of Nuclear Cardiology (ASNC) 2022 meeting was positive late-breaking data on the phase 3 Aurora trial for the flurpiridaz (F-18) PET radiotracer agent.

September 12, 2022

Siemens debuts new, cleared SPECT/CT model

Siemens Healthineers splashed an FDA-approved SPECT/CT system June 12 at the 2022 annual meeting of the Society of Nuclear Medicine & Nuclear Imaging in Vancouver, B.C.

June 14, 2022

American Society of Nuclear Cardiology says AHA/ACC chest pain guidelines miss the mark

One of the group's primary concerns is the "inappropriately large role" given to FFR-CT. 

October 29, 2021
insurance

‘A troublesome trend’: Top imaging groups slam insurer-directed test substitution policies

Advocates say payers' push for single first-line imaging tests for all patients isn't backed by evidence and may cause harm.

September 27, 2021
District of Columbia DC congress capitol hill

Imaging advocates, bipartisan lawmakers unite to oppose ‘misguided and massive’ Medicare pay cuts

Congressmen highlighted a planned wage increase for clinical labor that will spell 20% reductions elsewhere, due to budget neutrality. 

September 1, 2021
scholz.jpg

Medical isotope specialist NorthStar announces new executive hire

Frank Scholz, PhD, will oversee the Beloit, Wisconsin, firm's Mo-99 expansion efforts and new radioisotope development programs, among other duties.

June 21, 2021

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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