Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

FDA fast-tracks empagliflozin for treatment of chronic HF

The FDA on June 26 granted Boehringer Ingelheim and Eli Lilly and Company’s drug empagliflozin Fast Track designation for the treatment of chronic heart failure, the companies announced.

June 27, 2019

The average person is just 4 degrees of separation from heart failure

One in five Americans are able to recognize the symptoms of heart failure, according to a new survey from Abbott—a troublesome finding considering the same research puts the average individual just four degrees of separation from HF.

June 19, 2019
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Stem cell patches rejuvenate damaged heart muscle after MI

Researchers at Imperial College London have developed a sew-on heart patch that leverages stem cells to support and repair heart muscle after a heart attack—something that could dramatically lower MI survivors’ risk of future heart failure.

June 4, 2019

HF patients less likely to follow treatment advice if they’re lonely

Loneliness, above all else, was an independent predictor of whether patients stuck to their doctors’ guidelines.

June 3, 2019

COAPT: Patients with HF, mitral regurgitation see better health outcomes with TMVR

A recent analysis of the COAPT trial, published this spring in the Journal of the American College of Cardiology, suggests patients with symptomatic heart failure (HF) and secondary mitral regurgitation (MR) might see better mental and physical outcomes if they’re treated with edge-to-edge transcatheter mitral valve repair (TMVR) in lieu of standard therapy.

May 30, 2019

Fertility treatment linked to peripartum cardiomyopathy

The risk of peripartum cardiomyopathy (PPCM) is up to five times higher in mothers who undergo common fertility treatments like intracytoplasmic sperm injection (ICSI) and in vitro fertilization (IVF), according to data presented at Heart Failure 2019 in Athens.

May 28, 2019

Abiomed’s Impella RP system is safe, FDA says

Results from the FDA’s latest investigation into Abiomed’s Impella RP system are in—and, with a couple of caveats, they’re positive.

May 22, 2019
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How to alleviate patient anxiety about ICDs

A six-week online training course centered around living with an implantable cardioverter-defibrillator (ICD) helped alleviate anxiety in heart failure patients who were apprehensive about their devices.

May 21, 2019

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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