ACC unveils 2013 late-breakers

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 - clinical trial

The American College of Cardiology (ACC) has released its lineup of late-breaking clinical trials that will be featured at its 2013 annual scientific meeting, March 9 through 11 in San Francisco. C ardiovascular Business will be there to bring you daily coverage of the presentations.

The schedule includes:

March 9: Opening showcase and late-breaking clinical trials

  • Final results of Randomized Trial of Left Atrial Appendage Closure Versus Warfarin for Stroke/Thrombolembolic Prevention in Patients with Non-Valvular Atrial Fibrillation
  • HPS2-THRIVE: Randomized Comparison of  Extended Release Niacin/Laropiprant 2 g Daily Versus Placebo in 25,673 Patients at High Risk of Occlusive Vascular Events

March 10: Interventional

  • Early High Dose Rosuvastatin for Contrast-induced Nephropathy Prevention in Acute Coronary Syndrome
  • A Randomized Evaluation of the SAPIEN XT Transcatheter Valve System in Patients with Aortic Stenosis Who Are Not Candidates for Surgery: PARTNER 2, Cohort B Outcomes
  • One-Year Outcome of a Trial Comparing Second Generation Drug-eluting Stents Using Either Biodegradable Polymer of Durable Polymer: the NOBIRITM Biolimus-eluting vs. XIENCETM/PROMUSTM Everolimus-eluting Stent Trial (NEXT)
  • CHAMPION PHOENIX Trial, main results

March 10: Chronic CAD/stable ischemic heart disease and acute coronary syndromes

  • The STREAM Trial
  • Early Administration of Eplerenone in Patients with Acute MI Without Heart Failure: Results of the Randomized, Double-Blind, Placebo-Controlled REMINDER Trial
  • Effects of the P-Selectin Antagonist Inclacumab in the Select-Acute Coronary Syndrome Trial
  • Randomized Comparison of High-dose Oral Vitamins vs. Placebo in the Trial to Assess Chelation Therapy
  • Evaluation of Ranolazine in Patients with Type 2 Diabetes Mellitus and Chronic Stable Angina (TERISA): A Randomized Clinical Trial

March 11: General Cardiology

  • Three-year Outcomes after Transcatheter or Surgical Aortic Valve Replacement in High-Risk Patients with Severe Aortic Stenosis
  • A Randomized Trial to Compare Percutaneous Coronary Intervention Between Massachusetts Hospitals with Cardiac Surgery Onsite and Community Hospitals without Cardiac Surgery Onsite
  • The German Off-pump Coronary Artery Bypass Grafting in Elderly Patients (GOPCABE) Study
  • CORONARY: The CABG Surgery Off or On Pump Revascularization Study, One-year Results
  • PRAGUE-6 Trial: Off-pump Versus On-pump Coronary Artery Bypass Graft Surgery in Patients with EuroSCORE equal to or greater than 6

March 11: Heart Failure

  • The St. Vincent’s Screening to Prevent Heart Failure Study: Impact of Natriuretic Peptide Guided Screening and Treatment on Long-term Prevalence of Left Ventricular Dysfunction, Heart Failure and Cardiovascular Events
  • Digoxin Reduces 30-day All-cause Hospital Admission in Ambulatory Older Patients with Chronic Heart Failure and Reduced Ejection Fraction
  • The ASTRONAUT study: Aliskiren Trial on Acute Heart Failure outcomes
  • Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Diastolic Heart Failure (RELAX) Trial