Clinical Research

While a vast majority of heart transplants in the United States are successful, unplanned hospitalizations after the procedures are still incredibly common. Top 10 reasons for readmission after heart transplant.

SAVR associated with ‘excellent’ long-term survival rates, new research confirms

Even as TAVR continues to build momentum as the go-to treatment option for many patients, researchers are keeping a close eye on the long-term safety and effectiveness of SAVR.

October 18, 2023
A late-breaking science presentation at the annual TCT interventional cardiology meeting.

Late-breaking clinical trials at TCT 2023

Here is a list of all the late-breaking clinical trials being presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2023 annual meeting Oct. 23-26, 2023, in San Francisco.

October 17, 2023
The central figure from the study "Predictors and Variation in Cardiac Rehabilitation Participation After Transcatheter Aortic Valve Replacement study 2023," showing the wide variation in the percentage of patients who receive post-TAVR rehab among TAVR patients in Michigan.

Less than one-third of TAVR patients enter cardiac rehab

Only about 30% of patients who underwent TAVR in Michigan participated in cardiac rehabilitation within 90 days after discharge.

October 16, 2023
Direct acyclic graph representing a causal structural model of mediation of the association between obesity in early pregnancy and cardiovascular disease (CVD) risk factors after delivery. E indicates exposure; GDM, gestational diabetes; HDP, hypertensive disorders of pregnancy; M, mediators; O, outcome; PTB, preterm birth; SBP, systolic blood pressure; SGA, small-for-gestational-age birth; and TC, total cholesterol. *Variable included in sensitivity analysis.

Pregnancy complications increase and unmask cardiovascular risks in obese patients in NIH study

New research is providing a broader understanding of how cardiovascular disease risk manifests following pregnancy. Having obesity before and during early pregnancy appears to be a strong indicator of risk for developing future cardiovascular disease and was significantly linked with adverse outcomes during pregnancy.

October 16, 2023
Specialists at Cleveland Clinic treated a hypertrophic cardiomyopathy patient with a new gene therapy from Tenaya Therapeutics. Researchers hopes this first-in-class gene therapy, known as TN-201, can restore the patient’s MYBPC3 levels and eventually lead to disease reversal.

Cleveland Clinic treats first patient with new gene therapy for hypertrophic cardiomyopathy

Researchers hopes this first-in-class gene therapy, known as TN-201, can restore the patient’s MYBPC3 levels and eventually lead to disease reversal.

October 13, 2023
Blood pressure

No, a popular blood pressure medication does not increase heart failure risk, new research confirms

Dihydropyridines such as amlodipine have been the topic of some debate in recent months due to fears they lead to significant side effects. 

October 13, 2023
AI artificial intelligence stethoscope doctor

AI model detects multiple heart issues in a single 10-second audio clip

The advanced algorithm achieved a sensitivity of 93% and specificity of 98%. It was trained to identify up to five different valvular diseases at the same time from a single audio clip.

October 10, 2023
Patisiran, marketed under the name Onpattro

FDA chooses not to approve patisiran for treating ATTR cardiomyopathy

The announcement came just weeks after an FDA subcommittee voted in favor of approval. 

October 9, 2023

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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