Structural & Congenital Heart Disease

SAN DIEGO — General and local anesthesia are comparably safe and effective during transcatheter aortic valve replacement (TAVR) procedures, according to the first randomized trial to compare the two approaches.

Compared to heart failure patients with severe secondary mitral regurgitation who were treated with guideline-directed medical therapy alone, those randomized to a MitraClip procedure plus optimal medical therapy demonstrated relative reductions of 47 percent for heart failure hospitalizations and 38 percent for mortality at two years of follow-up.

Sustained elevated blood pressure can increase a patient’s risk for both aortic valve stenosis and aortic regurgitation, according to an analysis of 5.4 million non-CVD patients in the U.K.

Gregg W. Stone, MD, had the unenviable task of condensing the 255-page agenda for next weekend’s Transcatheter Cardiovascular Therapeutics (TCT) meeting into a handful of highlights during a 12-minute media briefing on Thursday, Sept. 13.

Three decades after the first Transcatheter Cardiovascular Therapeutics conference, TCT.18’s organizers are moving “toward a more practical approach,” says Cardiovascular Research Foundation CEO Juan Granada, MD.

Minimally invasive cardiac surgery without peripheral cannulation is both safe and effective for correcting a wide range of congenital heart defects, including mitral valve repair and pulmonary stenosis, according to research published in Heart, Lung and Circulation this week.

Research out of Australia suggests newborns with congenital heart disease (CHD) are likely to have enlarged kidneys at birth—a finding that could help alert physicians to organ abnormalities before a child is born.

Early discharge following TAVR is associated with fewer readmissions and similar mortality over the following 30 days compared with a standard discharge strategy, according to a meta-analysis published in JACC: Cardiovascular Interventions.

Mothers or infants experienced no adverse cardiac events during 24 pregnancies completed by women who had undergone an arterial switch operation, according to a single-center, retrospective study published online Sept. 5 in JAMA Cardiology.

A learning curve of at least 225 procedures is required for hospitals to perform transcatheter aortic valve replacements (TAVRs) with the lowest mortality rates, suggests a study of 16 centers participating in an international registry.

Patients hospitalized with endocarditis can be safely switched from intravenous antibiotics to oral medication about halfway through the course of treatment, according to a randomized trial published in the New England Journal of Medicine.

Cardiac patients who develop new-onset atrial fibrillation (AFib) after transcatheter aortic valve replacement (TAVR) are at a higher risk for complications like stroke, myocardial infarction and death than those whose AFib was established before the procedure, researchers report in the current online issue of JACC: Cardiovascular Interventions.