Structural & Congenital Heart Disease

A new study published in Circulation emphasized the importance of prompt arterial switch operations (ASOs) for infants with transposition of the great arteries, as neonates more than 6 days old were 90 percent more likely to die in the perioperative period.

Under the United Nations’ Sustainable Development Goals, a blueprint for global well-being penned in 2015, officials aim to end all preventable deaths in newborns and children under 5 by 2030. And to Jackie Boucher, MS, BS, president of Children’s HealthLink in Minneapolis, that means better understanding congenital heart disease (CHD).

A miniature pacemaker developed for use in infants and those with limited vascular access has passed a proof-of-concept simulation and is entering its second phase of testing, researchers from Children’s National Health System in Washington, D.C., have reported.

Antibiotic prescriptions to prevent infective endocarditis (IE) decreased following a 2007 guideline update from the American Heart Association—even among high-risk patients for whom antibiotics were still recommended. Those patients showed an estimated 177 percent increase in IE incidence over the next several years, according to a new study.

Automated cardiac valve tracking halved the analysis time and variability in blood-flow quantification with four-dimensional (4D) flow MRI, researchers reported in Radiology. The algorithm may help clinicians more efficiently assess the severity of congenital and valvular heart disease, they said.

Eight European scientific societies joined forces to produce what they say is the first interdisciplinary position paper to help clinicians manage patients with patent foramen ovales (PFOs).

Hospitals offering transcatheter aortic valve replacement (TAVR) tend to produce the best survival outcomes when both TAVR and surgical AVR (SAVR) caseloads remain high, according to a study published Oct. 31 in JAMA Cardiology.

Kidney dialysis is an independent predictor of mortality in end-stage renal disease (ESRD) patients undergoing transcatheter aortic valve implantation (TAVI), according to a seven-year trial of 2,000 men and women in Karlsruhe, Germany.

The American Heart Association and Children’s Heart Foundation are dedicating $776,000 to four upcoming research projects focused on congenital heart defects (CHDs), the AHA announced in late October.

Intermediate-risk transcatheter aortic valve replacement (TAVR) patients see fewer strokes, deaths and encephalopathies than those who undergo surgical aortic valve replacement (SAVR), researchers reported in the Oct. 30 edition of the Journal of the American College of Cardiology.

A new study published in the Journal of the American College of Cardiology provides reassurance that TAVR is a safe alternative to surgical aortic valve replacement (SAVR) in low-risk patients, as zero of the 200 people undergoing the transcatheter procedure died or experienced a disabling stroke within 30 days.

Nonfemoral access routes for transcatheter aortic valve replacement (TAVR) are associated with significantly higher 30-day mortality rates for frail patients but not among other older adults, according to a post hoc analysis of the FRAILTY-AVR study published in JACC: Cardiovascular Interventions.