Structural & Congenital Heart Disease

Mutations in the CHD4 gene are known contributors to congenital heart defects. Biologists at the University of North Carolina School of Medicine believe they are beginning to understand why.
Coronary artery bypass graft (CABG) surgeries, in particular, were strongly linked to the life-threatening condition—carrying a 14-fold increase in relative risk, among the top five of all inpatient procedures analyzed.
Acute kidney injury (AKI) occurs in about 9 percent of patients undergoing left atrial appendage closure (LAAC) and is associated with greater odds of downstream mortality and embolic events, according to a study published June 4 in JACC: Cardiovascular Interventions.
Patients who required permanent pacemakers (PPMs) after transcatheter aortic valve replacement (TAVR) demonstrated lower survival rates and higher comorbidity burdens over a multiyear follow-up. However, they didn’t accumulate significantly greater healthcare costs, according to a study published online May 25 in JAMA Network Open.
An investigational transcatheter mitral valve replacement (TMVR) device helped reduce mitral regurgitation to zero or trace levels in 98.7 percent of patients, according to 30-day follow-up data from the first 100 people scheduled to be treated with Abbott’s Tendyne system.
Despite being performed in an older population with more cardiovascular comorbidities, transcatheter aortic valve replacement (TAVR) demonstrated similarly low rates of postoperative stroke and mortality compared with surgical aortic valve replacement (SAVR) in a study of patients with previous strokes.
Although survival after congenital heart surgery is improving, patients who receive procedures for even mild defects have long-term mortality rates at least three times higher than their counterparts in the general population, according to a U.S.-based registry study published in the Journal of the American College of Cardiology.
Acetaminophen after pediatric heart surgery was associated with an increasingly protective effect against acute kidney injury (AKI), according to an analysis of separate cohorts at two children’s hospitals.
The first patient to be treated with a novel mitral valve repair system is recovering and showed no complications during a 30-day follow-up period, according to a press release issued by the system's developer.
A new study analyzed the “substantial” cost burden to state and federal healthcare programs from patients hospitalized with endocarditis because of drug abuse. Findings were presented April 26 at the Society for Cardiovascular Angiography and Interventions (SCAI) 2018 Scientific Sessions in San Diego.
Edwards Lifesciences has received CE mark approval for its Cardioband Tricuspid Valve Reconstruction System, making it the first commercially available transcatheter therapy to treat tricuspid valve heart disease.
With the opioid epidemic in full swing and many intravenous drug users likely to relapse and require even more challenging and expensive treatment, physicians are left to grapple with what to do about repeat cases of infective endocarditis.
A late-breaking study presented at SCAI 2018 demonstrated that patients who stay in the hospital for more than 72 hours after transcatheter aortic valve replacement (TAVR) are more likely to die in the following year than those with earlier discharges.
A post-approval study of Abbott’s MitraClip device showed positive one-year results for the first 2,000 patients entered into the national Transcatheter Valve Therapy registry, according to late-breaking science presented April 26 at SCAI 2018 in San Diego.
Apr 27, 2018 | Imaging
A small study presented at SCAI 2018 demonstrated the potential of 3D printing to help clinicians select the appropriate size for transcatheter heart valves and avoid paravalvular leak (PVL).
The first-ever risk score for predicting 30-day readmission rates in patients undergoing transcatheter aortic valve replacement (TAVR) can be easily folded into electronic medical records and inform perioperative care decisions, researchers reported at the Society for Cardiovascular Angiography and Interventions 2018 Scientific Sessions.
Transcatheter mitral valve replacement (TMVR) is associated with high rates of mortality in patients with severe mitral annular calcification, but survivors show significant improvements in heart-related symptoms.
Modifying the American Academy of Pediatrics’ (AAP) critical congenital heart disease (CCHD) screening algorithm to include one repeat pulse oximetry test instead of two could identify more infants with other serious diseases that require attention, according to a study published online April 24 in Pediatrics.
Children and young adults who were born with congenital heart disease (CHD) have an eight-fold risk of intracerebral hemorrhage (ICH) when compared to the general population, according to a Swedish study published online April 6 in Stroke. However, the absolute risk of hemorrhagic stroke remained low for both groups.
A country-wide examination of data in France showed a marked increase in transcatheter aortic valve replacement (TAVR) procedures, in addition to reduction in in-hospital mortality for all AVR subsets.
About 3 percent of patients undergoing transcatheter aortic valve replacement (TAVR) also have severe mitral stenosis and are at a greater risk of long-term adverse events, researchers reported in JACC: Cardiovascular Interventions.