Lipids & Metabolic | Cardiovascular Business

Lipids & Metabolic

Medicaid expansion linked to greater access to diabetes drugs

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States that expanded eligibility for Medicaid in 2014 and 2015 saw an immediate uptick in Medicaid prescriptions filled for diabetes treatments, suggesting the legislation played a direct role in improving access and adherence to those drugs.

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Early type 1 diabetes trims 18 years from women’s lives

Developing type 1 diabetes before the age of 10 shortens the lifespans of women by almost 18 years and of men by about 14 years, according to a Swedish registry study published in The Lancet.

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Coronary microvascular dysfunction tops BMI for CVD risk prediction

Coronary microvascular dysfunction (CMD) identified with cardiac stress PET testing was a better predictor of adverse events among obese patients than body mass index (BMI) and other traditional risk factors, researchers reported in the Journal of the American College of Cardiology.

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Red blood cell enzyme may promote endothelial dysfunction in diabetics

Swedish researchers have identified a potential mechanism for the endothelial dysfunction found in patients with type 2 diabetes (T2D): increased expression of the arginase I protein in red blood cells.

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Experts: Aiming for a diverse diet might increase total consumption

Consuming an array of foods sounds reasonable in theory but may ultimately backfire, according to the authors of a scientific advisory statement published online Aug. 9 in Circulation.

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Statins underused for the ‘other’ CAD: carotid artery disease

Continued use of statins was associated with a 25 percent reduced risk of major adverse cardiovascular events in patients after carotid revascularization, according to a Canadian study with five years of follow-up. But only about two-thirds of patients were taking moderate to high doses of the drugs prior to their procedures.

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Study shows cumulative impact of modest elevations in BP, LDL

Moderately elevated levels of LDL cholesterol and systolic blood pressure (SBP) that persist for a long time are just as dangerous as very elevated values over a shorter timeframe, according to a new study published in PLOS One.

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Dropping low LDL even further reduces CVD risk

Lowering LDL cholesterol (LDL-C) beyond guideline-recommended levels further reduces cardiovascular events without compromising safety, according to a meta-analysis published Aug. 1 in JAMA Cardiology.

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Waist measurement could ID patients best suited for heart failure drugs

A simple measure of waist circumference could identify chronic heart failure patients who would benefit most from mineralocorticoid receptor antagonists, according to a review published July 25 in JAMA Cardiology.

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Ex-nurse convicted of manslaughter after withholding insulin from inmate

A former jail nurse has been sentenced to 15 years in prison for manslaughter after she was found guilty of causing the death of a diabetic inmate who went a week without insulin.

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Experts call for more genetic testing of familial hypercholesterolemia

A panel of experts believes genetic testing of individuals at risk of familial hypercholesterolemia (FH) could “alter the natural history” of the condition, which is estimated to be undiagnosed in more than 27 million people worldwide, including more than one million in the United States.

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Higher BMI at young age increases BP, changes heart structure

Higher body mass index (BMI) as a young adult may result in higher blood pressure (BP) and left ventricle mass index, resulting in changes to the heart structure, researchers report in the American Heart Association’s (AHA) journal Circulation.

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FDA approves Abbott’s 14-day continuous glucose monitor

The FDA approved the FreeStyle Libre flash glucose monitoring system, which works for up to 14 days at a time, according to an announcement from device maker Abbott.

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High HDL levels in menopausal women may not be cardioprotective

Postmenopausal women with high levels of high-density lipoproteins (HDL) did not have the same cardioprotective benefits typically seen in women of other ages, researchers reported in the American Heart Association journal Arteriosclerosis, Thrombosis and Vascular Biology.

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Omega-3 fatty acids have minimum impact on cardiovascular health

A recent review of almost 80 randomized control trials suggests increased intake of long-chain omega-3 (LCn3) polyunsaturated fatty acids from oily fish have minimal to no effect on mortality or cardiovascular health. Results of the review were published online July 18 in the Cochrane Library.

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Tuberculosis vaccine shows potential as low-cost treatment for type 1 diabetes

Jul 13, 2018 | Lipids & Metabolic

A tuberculosis vaccine that has been around for a century is being investigated as a potential low-cost, long-term treatment for type 1 diabetes.

Lipids & Metabolic

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Gene editing slashes cholesterol in monkey study

Jul 12, 2018 | Lipids & Metabolic

A team of researchers used genome editing to inactivate the PCSK9 protein in the livers of rhesus macaque monkeys, resulting in 30 to 60 percent reductions in LDL cholesterol and even more significant drops in PCSK9 levels.

Lipids & Metabolic

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LDL aggregation: A modifiable marker of cardiovascular risk

Jul 12, 2018 | Lipids & Metabolic

A new study published in the European Heart Journal suggests a particular quality of LDL cholesterol—not just the concentration of it—influences a patient’s risk of cardiovascular disease.

Lipids & Metabolic

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When side effects are welcomed: Statins may double as flu fighters

Jul 10, 2018 | Lipids & Metabolic

On the heels of a deadlier-than-normal flu season, some scientists are wondering what will happen when a true pandemic hits. Vaccine doses would likely dry up—but cheap, readily available medications like statins could help a patient stave off flu as the virus runs its course, a pair of researchers told NPR.

Lipids & Metabolic

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Why does juice get a pass in the battle against sugary drinks?

Jul 09, 2018 | Lipids & Metabolic

Three pediatrics professors teamed up for an editorial in The New York Times imploring readers to lump juice into the unhealthy beverage category alongside soda.

Lipids & Metabolic

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Dietary policies in schools could prevent 22K annual US deaths

Jul 09, 2018 | Lipids & Metabolic

School programs that provide fresh fruits and vegetables and limit the availability of sugar-sweetened beverages (SSBs) could prevent an estimated 22,383 deaths due to cardiometabolic disease each year in the U.S., researchers calculated in a study published July 6 in PLOS One.

Lipids & Metabolic

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