Heart Failure

Tafamidis, Pfizer’s treatment for transthyretin amyloid cardiomyopathy (ATTR-CM), has been granted a priority review designation from the FDA, potentially speeding its path to approval.

Although childhood cancer survival has improved markedly over the past few decades, a new study out of the Netherlands suggests a greater proportion of those survivors are at risk of developing heart failure at young ages, due in part to cardiotoxic treatments.

A tool designed to assess the psychosocial status of heart transplant candidates may also be able to predict which left ventricular assist device (LVAD) recipients are at the highest risk of being readmitted to the hospital, Cleveland Clinic researchers reported Jan. 9 in Circulation: Heart Failure.

Women with heart failure with reduced ejection fraction (HFrEF) live longer than their male counterparts, but those additional years are plagued by a lower quality of life—including greater levels of self-reported anxiety, depression and physical disability—according to an analysis in the Journal of the American College of Cardiology.

AI applied to an electrocardiogram (EKG) test reliably detected asymptomatic left ventricular dysfunction (ALVD)—a precursor to heart failure—and predicted which patients were most at risk of developing the condition in the future, according to a Mayo Clinic study published in Nature Medicine.

A French health tech company debuted its Chronolife vest—a cotton- and lycra-based wearable aimed at preventing medical emergencies in patients with chronic or congestive heart failure (CHF)—at CES 2019 in Las Vegas on Jan. 6, CNET reported.

University of Chicago Medicine physicians performed the 16th and 17th triple transplant surgeries in the United States within 30 hours of each other in late December, giving two different patients a healthy heart, kidney and liver all at once.

Compared to drug therapy alone, catheter ablation nearly halved the risk of death and improved a range of clinical outcomes for patients with both heart failure and atrial fibrillation (AFib) in a meta-analysis.

Another study has linked the Hospital Readmissions Reduction Program (HRRP) to increased mortality among patients hospitalized for heart failure, prompting at least one cardiologist to urge policymakers to revise the policy.

Popular anti-diabetes drug metformin could have positive implications for heart failure patients, too, according to a recent study that found the medication reduced left ventricular stiffness in mice with heart failure with preserved ejection fraction (HFpEF).

Questioning older patients about their weight earlier in life could be a low-tech, low-cost way to better predict a person’s future risk of heart disease, according to a study published in the Journal of the American Heart Association.

Although efforts to reduce heart failure (HF)-related deaths and readmissions in the United States were successful in the early 2000s, rates of HF-related ER visits, comorbid hospitalizations and mortality are at a standstill in 2018, according to a nationwide study published Dec. 11 in Circulation: Heart Failure.