Acute Coronary Syndrome

People who are frail and older than 65 are at a 50 percent increased risk of major bleeding during hospitalizations for heart attack compared to nonfrail patients, according to research published Nov. 19 in JACC: Cardiovascular Interventions.

Major cardiology associations joined forces to update the 2012 universal definition of myocardial infarction and standardize what constitutes a heart attack.

A machine learning-based risk calculator developed to assess an individual’s long-term risk for atherosclerotic cardiovascular disease (ASCVD) identified 13 percent more high-risk patients and recommended unnecessary statin therapy 25 percent less often than standard risk assessment tools in initial tests, researchers reported in the Journal of the American Heart Association.

Results of the CIRT trial presented at the American Heart Association Scientific Sessions dimmed hopes that low-dose methotrexate can reduce cardiovascular events but furthered researchers’ understanding of which inflammation-targeting therapies might succeed in that regard.

Cancer is overtaking heart disease as the leading cause of death in the U.S., particularly in high-income counties, suggests a new analysis published in the Annals of Internal Medicine.

The Door-to-Unload pilot study concluded without any “prohibitive safety signals,” researchers reported at the American Heart Association 2018 Scientific Sessions, clearing the path for a larger trial to test the hypothesis that ventricular unloading prior to PCI with the Impella CP heart pump can reduce reperfusion injury.

VITAL and REDUCE-IT—both highly anticipated trials revolving around the cardiovascular benefits of fish oil products—delivered mixed results at this year’s AHA Scientific Sessions in Chicago, with one trial observing few heart benefits from omega-3s while the other saw a 25 percent reduction in major cardiovascular events with a purified eicosapentaenoic acid product.

Cocaine, amphetamines and cannabis could raise adolescents’ risk for acute myocardial infarction (AMI), in some cases increasing a teen’s odds for MI by up to seven times, according to research out of Shanghai Jiao Tong University School of Medicine in China.

Critical shortages of imaging equipment and qualified radiologists left an estimated 56,000 angina patients without access to potentially lifesaving computed tomography (CT) scans last year, the Royal College of Radiologists and British Society of Cardiovascular Imaging announced Nov. 8.

Poor health literacy could mean an increased risk of death for patients hospitalized with acute decompensated heart failure (ADHF), according to a study published in Mayo Clinic Proceedings Nov. 7.

A new study in JAMA Cardiology showed patients’ risk perceptions and willingness to accept therapy are influenced by the type of estimate they’re presented with and how that information is organized.

The FDA has approved canagliflozin (Invokana) to reduce the risk of major adverse cardiovascular events (MACE) including stroke, heart attack and cardiac death in patients with type 2 diabetes and established cardiovascular disease. It is the first oral diabetes medication to gain this indication, according to drug manufacturer Janssen Pharmaceutical Companies.