Acute Coronary Syndrome

A new biotech company out of Massachusetts is levering human genetics and genome editing to “turn the tide” of coronary artery disease (CAD), experimenting with CRISPR to stop CAD from ever developing in at-risk individuals.

A study of more than 750 kids who were followed into their thirties has linked oral infections in childhood to CVD later in life—particularly subclinical carotid atherosclerosis.

After a successful safety and feasibility trial run, the FDA granted approval April 26 to the STEMI DTU (ST-Elevation Myocardial Infarction Door-to-Unloading) study, which will examine whether unloading the left ventricle prior to reperfusion can reduce myocardial damage and lead to fewer CV complications in STEMI patients.

Nearly one in six young women who suffer a heart attack can’t be classified under the Fourth Universal Definition of MI, according to a study out of Yale University—but the majority can be accurately classified using a sex-specific taxonomy known as VIRGO.

A little less than half of atherosclerotic cardiovascular disease (ASCVD) patients are treated for blood cholesterol according to 2013 clinical guidelines, with around half missing out on a statin prescription the guidelines would have recommended, according to a study published in the American Journal of Cardiology.

Stress disorders like PTSD and adjustment disorder were linked to adverse cardiovascular outcomes in a recent BMJ study, Reuters reports, with the greatest CV risk posed in the months directly after a patient is diagnosed with such a condition.

MicroRNAs could be key to treating heart failure, according to a study out of Boston Children’s Hospital and Zhejiang University School of Medicine in China.

Antibiotic use—particularly regimens that last for two months or more—was linked to an increased risk of CVD in a recent study of nearly 36,500 older women.

A study of nearly 4,000 patients with coronary artery disease (CAD) has linked blood pressure variability (BPV) between clinic visits to significantly greater progression of coronary atheroma and major adverse events, suggesting BP stability might be an important factor in CAD care.

Eating a late dinner and skipping breakfast could raise heart patients’ risk of a repeat MI or death by up to fivefold, according to research published in the European Journal of Preventive Cardiology April 17.

The 71-year-old Framingham Heart Study has received $38 million from the National Heart, Lung, and Blood Institute to fund a new six-year study into the biology of aging.

More than 80% of stable patients with ST-segment elevation myocardial infarction (STEMI) are treated in the intensive care unit despite only 16% of them experiencing complications that require an ICU stay, according to a U.S. registry analysis published in JACC: Cardiovascular Interventions.