Cardiologist and wife killed in car accident—colleagues say he ‘represented the very best in medicine’

Alfred G. Valles, MD, an interventional cardiologist being remembered by colleagues after a tragic accident

Alfred G. Valles, MD. Image courtesy of The Heart Group, Cardiovascular Associates. 

Interventional cardiologist Alfred G. Valles, MD, was 50 years old at the time of the accident. According to colleagues, he "strived daily to achieve his vision for world-class care."

Pregnancy complications increase and unmask cardiovascular risks in obese patients in NIH study

Direct acyclic graph representing a causal structural model of mediation of the association between obesity in early pregnancy and cardiovascular disease (CVD) risk factors after delivery. E indicates exposure; GDM, gestational diabetes; HDP, hypertensive disorders of pregnancy; M, mediators; O, outcome; PTB, preterm birth; SBP, systolic blood pressure; SGA, small-for-gestational-age birth; and TC, total cholesterol. *Variable included in sensitivity analysis.

Figure from the study shows a direct acyclic graph representing a causal structural model of mediation of the association between obesity in early pregnancy and cardiovascular disease (CVD) risk factors after delivery. E indicates exposure; GDM, gestational diabetes; HDP, hypertensive disorders of pregnancy; M, mediators; O, outcome; PTB, preterm birth; SBP, systolic blood pressure; SGA, small-for-gestational-age birth; and TC, total cholesterol.

New research is providing a broader understanding of how cardiovascular disease risk manifests following pregnancy. Having obesity before and during early pregnancy appears to be a strong indicator of risk for developing future cardiovascular disease and was significantly linked with adverse outcomes during pregnancy.

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