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Structural & Congenital Heart Disease


Next-day discharge after minimalist transcatheter aortic valve replacement (TAVR) was safe for patients who didn’t experience perioperative complications and was linked to better one-year outcomes versus patients discharged later, according to a single-center study published in JACC: Cardiovascular Interventions.

The American Heart Association (AHA) and American College of Cardiology (ACC) rolled out new guidelines for managing valvular heart disease (VHD) in 2017, marking the second overhaul of VHD recommendations in three years—a move attributable to “extensive new data” that have shaped the way clinicians treat valve disease.

A larger valve option and more appropriate valve sizing using preprocedural imaging may eliminate the previously reported survival disparity between men and women undergoing transcatheter aortic valve replacement (TAVR), a new study in JACC: Cardiovascular Interventions suggests.

Procedures to replace or repair patients’ tricuspid valves (TVs) remain rare but have increased in recent years, according to a study in the Journal of the American College of Cardiology. But despite this increased volume, in-hospital mortality has remained steady at 8.8 percent.

The Centera transcatheter heart valve (THV) shows promise in addressing the “Achilles’ heel” of transcatheter aortic valve replacement (TAVR), according to Luis Nombela-Franco, MD, PhD, who wrote an editorial about the device’s pivotal study published in the Journal of the American College of Cardiology.


Recent Headlines

Birth weight strongly predictive of survival in infants with congenital heart disease

Infants with congenital heart disease (CHD) born post-term and with the most body weight have the best chance of surviving for five years, while lighter, preterm babies have poorer chances, according to new research.

Study: All Portico heart valve sizes demonstrate effective short-term performance

All sizes of the Portico TAVR system resulted in effective and safe short-term treatment of high-risk patients, according to a new study.

Risk of stroke in AFib patients associated with aortic curvature

Atrial fibrillation (AFib) heightens stroke risk—but new research shows that this is true only in people with certain aortic shapes. Those with aortic arches that are less curved are more prone to stroke, according to a study published online Aug. 1 in Nature.

Scientists use CRISPR to erase cardiomyopathy mutation in human embryos

CRISPR is capable of targeting specific stretches of genetic code and editing DNA. Researchers have used the tool to erase a genetic mutation that causes hypertrophic cardiomyopathy in human embryos.

Essential Frailty Toolset outperforms others in predicting mortality after TAVR, SAVR

Compared with six other scales that measure frailty, one called the Essential Frailty Toolset stands out for its ability to predict mortality 30 days after two types of valve replacement surgery. It can also predict worsening disability at one year, according to a new study.

Stroke is increasing in younger populations—but why?

With recent research suggesting that strokes among younger people are becoming more prevalent, healthcare professionals are looking into why.

Printing 3D hearts

3D printers have created the darnedest things: acoustic guitars that strum and guns that shoot, women’s high-heeled shoes, lights, clocks and even custom-fitted fabric.

AHA recognizes Penn Medicine cardiology researchers

The American Heart Association (AHA) has awarded Benjamin L. Prosser, PhD, a professor at the University of Pennsylvania, its Outstanding Early Career Investigator Award.

TAVR costs continue to rise while SAVR prices decline

Though the cost of surgical aortic valve replacement (SAVR) is decreasing, costs for transcatheter aortic valve replacement (TAVR) are rapidly growing, according to a new report from researchers at the University of California, Los Angeles.

A healthy heart could lead to a healthier brain later in life

Maintaining a heart-healthy lifestyle in young adulthood could help prevent brain shrinkage decades later, according to a new study by researchers at Northwestern University in Chicago.