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Structural & Congenital Heart Disease


Patients who received a mechanical prosthesis for surgical replacement of aortic or mitral valves derived a significant long-term survival benefit versus those who received a biologic prosthesis, according to a study in the New England Journal of Medicine.

Nearly half of all valve hospitals in the U.S. are misclassified as either low- or high-performing, according to research published in JAMA Cardiology—but that problem might have a simple fix.

DENVER — Transcatheter aortic valve replacement (TAVR) is an “economically dominant” strategy compared to surgical aortic valve replacement (SAVR) for patients with aortic stenosis at intermediate surgical risk, according to data presented by David J. Cohen, MD, MSc, Oct. 31 at the Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.

Research examining 278 patients with in-stent restenosis (ISR) found that drug-eluting balloon (DEB) was non-inferior in comparison with drug-eluting stent (DES) in terms of six-month minimal lumen diameter (MLD).

DENVER — Measuring frailty could lead to more accurate predictions of outcomes following transcatheter aortic valve replacement (TAVR) than a validated risk algorithm, according to research presented Oct. 30 at the annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.


Recent Headlines

More good news on TAVR

Just-released studies shine more positive light on TAVR in terms of durability five years out and long-term survival, with women outpacing men by about 15 percent.

Researchers ID new subset of patients who may benefit from aortic valve replacement

Clinical guidelines don’t recommend valve replacement for patients with severe aortic stenosis (AS) demonstrating normal flow and low gradients. But maybe they should, according to new research published in JACC: Cardiovascular Imaging.

Long-term survival after TAVR higher in women—despite initial complications

Despite encountering more short-term complications after transcatheter aortic valve replacement (TAVR), women have better long-term survival rates than men, according to a meta-analysis of 47,188 patients. However, they remain at greater risk for stroke.

JACC publishes appropriate use criteria for treating severe aortic stenosis

Published online Oct. 17 in the Journal of the American College of Cardiology, the guidelines offer recommendations on when to use transcatheter aortic valve replacement (TAVR), surgical aortic valve replacement (SAVR) or neither—and when either technique may be appropriate.

TAVR carries low dialysis risk for most kidney patients

Relatively few patients with chronic kidney disease (CKD) require dialysis after undergoing transcatheter aortic valve replacement (TAVR), according to a new study.

Fever during pregnancy linked to heart defects, facial deformities in baby

A new study published in the journal Science Signaling suggests fever during pregnancy is directly related to the development of heart defects and facial complications like cleft lip and palate, a phenomenon that might be managed with something as simple as Tylenol.

Growth-accommodating implant could change the field of pediatric surgery for the better

A medical implant that can expand internally to accommodate a child’s growth could be revolutionizing the field of pediatric surgery, according to a Massachusetts-based research team.

Newborns with congenital heart disease at increased risk for neurodevelopmental disabilities

Infants born with congenital heart disease (CHD) could be at increased risk for neurodevelopmental disabilities even before undergoing initial open-heart surgery, a new study published in NeuroImage: Clinical states.

Long-term survival rates after Ross procedure positive 25 years later

Adults who underwent the Ross procedure saw overwhelmingly “excellent” long-term outcomes 25 years later, according to a study published in the Journal of the American College of Cardiology.

Percutaneous mitral valve repair safe, effective in frail patients

Patients classified as frail who undergo percutaneous mitral valve repair (PMVR) demonstrate greater short-term improvement in quality of life than their nonfrail counterparts and similar improvements in six-minute walking distance and functional status, a new study found.