Pushing the Limits of Science and Technology

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The Basic/Translational Science Forum is an all day program comprised of state-of-the-art talks relevant to experimental electrophysiology, mechanisms of heart rhythm disorders and novel therapeutics. This year’s forum places particular emphasis on novel experimental model systems using emerging technologies and strategies relevant to arrhythmia mechanisms and therapy.

Novel Imaging Techniques
Chair: Andre G. Kleber, MD, University of Bern, Dept of Physiology, Bern, Switzerland

Optical Nanosensors
Heather A. Clark, PhD. Draper Laboratory, Cambridge, Mass.

Biophotonic Imaging of the Human Heart
Igor R. Efimov, PhD, Washington University, Biomedical Engineering, St. Louis

ECG Imaging
Yoram Rudy, PhD, Washington University, St. Louis, St. Louis, MO

Moderated Discussion | Thinking Fast: High Throughput Screens
Chair: Craig T. January, MD, PhD, University Of Wisconsin Hospital and Clinic, Madison, Wis.

High Throughput Screens — High Throughput Proteomics and Cardiovascular Disease
Arthur M. Brown, MD, PhD. ChanTest, Inc., Cleveland

High Throughput Drug Screening Using Engineered Heart Tissue
Thomas Eschenhagen, MD. University of Hamburg, Hamburg, Germany

High Throughput Screening Using Zebrafish
Calum A. MacRae, MD. Massachusetts General Hospital, Charlestown, Mass.

Moderated Discussion | Thinking Small: Nanotechnology
Chair: Kevin Kit Parker, PhD. Harvard University, Cambridge, Mass.

Nanotechnology and Cardiovascular Disease
Denis Buxton, PhD. NHLBI, Bethesda, Md.

Biomaterials and Cardiac Therapy
Andre G. Kleber, MD, University of Bern, Dept of Physiology, Bern, Switzerland

Nanofabrics and ECM Assembly
Kevin Kit Parker, PhD, Harvard University — Div of Engineering and Applied Science, Cambridge, Mass.

Moderated Discussion | Thinking Big: Large Animal Models of Disease
Chair: Raymond E. Ideker, MD, PhD, University of Alabama, Birmingham, Ala.

Disease — Insights from Rabbit Arrhythmic Models
Gideon Koren, MD. Rhode Island Hospital, Providence, R.I.

Disease — Large Animal Models of Disease: Spinal Cord Stimulation and AF Prevention
Gregory E. Morley, PhD. New York University School of Medicine, New York City

Moderated Discussion | New Approaches to Cardiac Regeneration
Chair: Michael Laflamme, MD, PhD, University of Washington, Seattle

Directed Differentiation of Human Stem Cells through Chemical Biology
Marc Mercola, PhD. Sanford Burnham Medical Research Institute, La Jolla, Calif.

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
Benoit G. Bruneau, PhD. University of California San Francisco, San Francisco

Engineering a Bioartificial Heart
Doris Taylor, MD, University of Minnesota, Minneapolis

Moderated Discussion | 2011 Douglas P. Zipes Lecture — Heart to Heart: Cardiospheres for Myocardial Regeneration
Eduardo Marban, MD, PhD, Cedars-Sinai Medical Center, Los Angeles