Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Keto diet ‘does not fulfill the criteria of a healthy diet,’ could be harmful for heart patients
The popular high-fat, low-carb diet is associated with multiple short-term benefits, but they appear to diminish over time.
Bayer subsidiary granted FDA’s fast track designation for new congestive heart failure treatment
AskBio, acquired by Bayer for more than $2 billion in 2020, is enrolling patients for a new clinical trial focused on the therapy's effectiveness in adult patients with non-ischemic cardiomyopathy and heart failure.
2 out of 5 AFib patients develop heart failure later in life
Stroke is typically seen as the biggest danger for patients after they receive an AFib diagnosis. This study, however, suggests heart failure could be an even bigger threat.
FDA announces new recall of Abbott’s HeartMate LVADs after 14 deaths
The issue at the center of this recall, which includes both the HeartMate II and HeartMate 3 LVAD, is the gradual buildup of biological materials. This can impact the device's performance, creating a heightened risk of injury or death.
Inter-atrial shunt in RELIEVE-HF improves symptoms in HFrEF, but not HFpEF
Gregg Stone, MD, explains the details of the late-breaking RELIEVE-HF trial at ACC.24, where an inter-atrial shunt improved symptoms in HFrEF, but not in HFpEF patients.

Since the first U.S. deceased after circulatory death (DCD) heart transplant in late 2019, there has bee ongoing research to determine the best way to utilize this new source of donor hearts. Researchers at Stanford University School of Medicine recently published a study in JAMA Network Open about their use of beating heart transplant procedures. It was found to be safe and had additional benefits. By avoiding additional warm and cold ischemic periods it eliminated need for ECMO.

New DCD heart transplant technique could reduce risk of serious injury

This new approach to transplanting deceased after circulatory death (DCD) hearts may offer significant benefits.

March 19, 2024

Elderly patient doctor. Despite an expanded indication from the FDA and lower prices, patient access to these cholesterol-lowering medications remains a significant issue.

Cognitive impairment among heart failure patients: How cardiologists can help

The Heart Failure Society of America shared a new scientific statement about this topic, noting that many patients may require additional help.

March 13, 2024

Abbott recalls device for tracking LVAD data after 8 injuries

This is a Class I recall, which means using the device “may cause serious injuries or death.” However, the FDA emphasized that this is a correction and not a product removal.

March 11, 2024

Family man from Netherlands named world’s longest-surviving heart transplant recipient

The 57-year-old father of two is still in good health decades after receiving a new heart.

March 4, 2024

Gen 2 Aria CV Pulmonary Hypertension System implanted in patient for first time.

World’s first patient treated with new implantable device for pulmonary hypertension

The procedure, performed on Feb. 14, was part of an early feasibility trial developed with help from the FDA.

February 29, 2024

Left, the FIRE1 heart failure remote monitoring device that gets implanted into the IVC to measure fluid volume status. Right, the external belt monitoring device worn by the patient that can alert clinicians about status changes so interventions can be done before a patient requires a hospital admission.

Early feasibility study for implantable heart failure monitor moves forward

Startup vendor FIRE1 completed patient enrollment in its U.S. early feasibility study for a heart failure remote monitoring device that directly measures fluid volume inside the IVC.

February 28, 2024

Regularly eating avocados is associated with a reduced risk of cardiovascular disease, according to a new study.

Top 5 diets for heart health: Expert panel puts Mediterranean, DASH at the top

The Ornish diet, a plant-based option developed to help prevent heart disease, also made the final ranking.

February 26, 2024

Multiple factors can interfere with pulse oximetry accuracy including skin pigmentation. Multiple studies have shown the inaccuracy of current pulse oximeters in patients with darker skin tones than whites, often over estimating their oxygenation when in fact they are hypoxic. Images courtesy of Masimo.

Inaccurate pulse oximeter readings impact Black heart failure patients and FDA plans to address this

Black patients are already less likely to receive LVADs or transplants compared to whites, and these inaccurate readings can further widen the disparities.

February 21, 2024

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Heart Failure

Keto diet ‘does not fulfill the criteria of a healthy diet,’ could be harmful for heart patients

Bayer subsidiary granted FDA’s fast track designation for new congestive heart failure treatment

2 out of 5 AFib patients develop heart failure later in life

FDA announces new recall of Abbott’s HeartMate LVADs after 14 deaths

Inter-atrial shunt in RELIEVE-HF improves symptoms in HFrEF, but not HFpEF

Around the web