Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Eko Health, the California-based healthcare technology company known for its advanced stethoscopes, has received U.S. Food and Drug Administration (FDA) approval for a new artificial intelligence (AI) offering designed to detect low ejection fraction (EF).

FDA approves new AI model for detecting signs of heart failure with a stethoscope

Eko Health worked closely with Mayo Clinic to develop and evaluate its latest AI offering. “Importantly, since a stethoscope is small and portable, this technology can be used in urban and remote locations," one clinician said. 

April 2, 2024
Newsweek ranked the 50 best heart hospitals in the world

Moderate prosthesis-patient mismatch after SAVR linked to worse long-term outcomes

The long-term impact of moderate PPM remains unclear. To learn more, researchers explored dozens of different studies from over the years, sharing their work in the Journal of the American Heart Association.

April 1, 2024
doctor examines patient data on their tablet

Donor hearts more likely to be accepted when the transplant candidate is female or white

"This finding suggests racial and gender bias as a potential contributor to the organ acceptance decision-making process," researchers wrote in JAMA.

March 29, 2024
Blood pressure

FDA approves new drugs for pulmonary arterial hypertension from Johnson & Johnson, Merck

Cardiologists now have two more tools to help them combat PAH, a rare vascular condition that often leads to heart failure.

March 27, 2024
Money dollar investments

Novo Nordisk to acquire biotech company working on new heart failure drug for $1.1B

Cardior Pharmaceuticals in Germany has been developing a new compound it says can “halt and partially reverse cellular pathology” in heart failure patients. 

March 25, 2024
2024 has been a banner year for structural heart treatments, especially those focused on the tricuspid valve. In February, for example, Edwards Lifesciences made history when its Evoque transcatheter tricuspid valve replacement (TTVR) system became the first device of its kind to gain U.S. Food and Drug Administration (FDA) approval for treating tricuspid regurgitation (TR). Two months later, Abbott’s TriClip transcatheter edge-to-edge repair (TEER) system also gained FDA approval for the treatment of TR.

A possible remedy for cardiology’s staffing shortages: heart failure internists

Internal medicine physicians spend a lot of time working with heart failure patients. A new commentary in JACC: Heart Failure explored the potential impact of providing IM trainees with special training so that they can deliver additional value.

March 21, 2024
The U.S. Food and Drug Administration (FDA) has announced that Abiomed is recalling its instructions for certain Impella left-sided blood pumps due to significant safety concerns. New and revised instructions for use (IFU) have been sent to all affected customers.

FDA announces new recall impacting more than 66,000 Impella heart pumps after 49 deaths

More than 100 patients have been seriously injured as a result of a significant safety concern. The Impella devices can still be used, according to the recall, if customers refer to Abiomed's new and revised instructions for use.

March 21, 2024
COVID-19 vaccine vaccination myocarditis heart damage inflammation RSNA imaging radiology cardiology

‘Highly effective’: COVID-19 vaccines reduced risk of heart failure, other cardiovascular complications after infection

Researchers explored data from more than 20 million adults for the new study, tracking both short- and long-term outcomes. 

March 20, 2024

Around the web

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