TCT Video: RAPID MI-ICE trial show promise for pre-reperfusion hypothermia

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TCT Video: RAPID MI-ICE Principal Investigator Goran Olivecrona, MD

Principal Investigator Goran K. Olivecrona, MD, PhD, of the Lund University Hospital in Lund, Sweden, outlines the results of the RAPID MI-ICE (Rapid Intravascular Cooling in MI as Adjunctive to PCI) trial, which assessed the safety and feasibility of rapidly induced hypothermia prior to reperfusion in STEMI patients.

The trial results, presented Sept. 23 at the 22nd annual Transcatheter Cardiovascular Therapeutics (TCT) conference, proved that hypothermia—a combination of a rapidly infused iced saline solution and a cooling catheter placed into the vena cava inferior—reduced infarct size by 38 percent and safely reached temperatures of less than 35 degrees Celsius before reperfusion.