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Endovascular treatment has emerged as the best thing since intravenous tissue plasminogen activator (IV t-PA) for acute ischemic stroke after five recent studies showed positive outcomes. Stent retrievers starred in the trials, with imaging playing a critical supporting role. But in clinical practice, which neuroimaging method best identifies likely beneficiaries is up for debate.
The fab five
It all started with MR CLEAN. MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) found that acute ischemic stroke patients who had proximal intracranial occlusions and received endovascular therapy along with standard care were more likely to achieve functional independence by three months than counterparts...