Wednesday, September 01 2010
The use of a seven-day, double-dose of clopidogrel reduced cardiovascular events and stent thrombosis in patients with acute coronary syndromes undergoing PCI, but resulted in higher bleeding rates, according to a substudy of the CURRENT-OASIS 7 trial presented at the European Society of Cardiology (ESC) congress in Stockholm and simultaneously published in the Lancet.
Tuesday, August 31 2010
A low-dose regimen of unfractionalted heparin compared with standard dose did not reduce the risk of major peri-PCI bleeding or vascular access site complications in patients receiving the anticoagulant fondaparinux, which had previously been found to cut bleeding by half, according to the results of the FUTURA/OASIS-8 trial presented at the European Society of Cardiology (ESC) congress in Stockholm, and simultaneously published in the Journal of the American Medical Association.
Tuesday, August 31 2010
Members of the AVERROES trial data monitoring committee ordered that the trial be halted after interim results found a 50 percent stroke reduction for apixaban (Bristol-Myers Squibb/Pfizer) compared to aspirin in patients with atrial fibrillation (AF) who were not suitable for warfarin, according to a presentation during the European Society of Cardiology (ESC) congress Aug. 31 in Stockholm.
Monday, August 30 2010
Clinical descriptors can assist clinicians in identifying high-risk patients within the range of risk for outpatients with atherothrombosis, according to a substudy of the REACH trial, presented this week at the European Society of Cardiology (ESC) conference in Stockholm, and simultaneously published in the Journal of the American Medical Association.
Monday, August 30 2010
Dabigatran (Pradaxa, Boehringer Ingelheim) was effective in preventing stroke in patients with atrial fibrillation, based on a post-hoc analysis of the randomized RE-LY trial. The analysis, presented at this week's European Society of Cardiology (ESC) congress in Stockholm, and simultaneously published in the Lancet, also showed that local standards of care affect the benefits of switching to new treatments.
Monday, August 30 2010
Administering low-dose supplements of n-3 fatty acids—eicosapentaenoic acid and docosahexaenoic acid or alpha-linolenic acid—did not significantly alter the rates of major cardiovascular (CV) events among MI patients, according to the results of the Alpha Omega trial presented this week at the European Society of Cardiology (ESC) meeting in Stockholm, and simultaneously published online Aug. 29 in the New England Journal of Medicine.
Monday, August 30 2010
Patients with acute coronary syndrome who underwent PCI and carry both the ABCB1 and CYPC2C19 genotypes are at an increased risk for cardiovascular death, MI and stroke. However, ABCB1 genotypes seem to be independent of clinical outcomes when patients are treated with prasugrel, but increased risk when patients are treated with clopidogrel, according to the results of a substudy of the TRITON-TIMI 38 trial presented this week at the European Society of Cardiology (ESC) meeting in Stockholm, and simultaneously published in the Lancet.
Thursday, July 29 2010
Written by Mary Stevens
BOSTON--Most stakeholders agree that the current U.S. model of healthcare is unsustainable, said keynote speaker Joseph Smith, MD, PhD, chief medical and science officer at West Wireless Health Institute in La Jolla, Calif., during his remarks at the World Congress Second Annual Leadership Summit on mHealth July 29.
Thursday, July 22 2010
Written by Chris Kaiser
PHILADELPHIA—What began as single-slice CT scanning has now evolved into dynamic volume scanning, utilizing as many as 320 detectors. The possibilities for wide-area detector technology include consistently low radiation exposure for coronary CT angiography (CCTA), as well as myocardial perfusion imaging, kinetic opacification slopes that distinguish between normal and diseased arteries and vascular profiling, according to Frank Rybicki, MD, PhD, who spoke July 21 at the annual meeting of the American Association of Physicists in Medicine (AAPM).
Tuesday, July 20 2010
PHILADELPHIA—Radiation scatter about the patient during abdominal fluoroscopic procedures is not isotropic, and staff would receive reduced dose if positioned at the head or feet, rather than laterally, according to a study presented July 19 at the annual meeting of the American Association of Physicists in Medicine (AAPM).
Tuesday, July 20 2010
Written by Chris Kaiser
PHILADELPHIA—Six years ago, Jim Donnelly was told the cancer on his tongue and larynx needed to be surgically removed. Not accepting that opinion, Donnelly, a professor of business at the University of Kentucky, Lexington, decided to go to the Mayo Clinic in Rochester, Minn. As was evident by the standing ovation following his address at the annual meeting of the American Association of Physicists in Medicine (AAPM), Donnelly has not lost his ability to speak, nor his sense of humor.
Monday, July 19 2010
Computer-aided analysis (CAA) showed high sensitivity and high negative predictive value for the evaluation of significant coronary artery disease (CAD) on 64-slice cardiovascular CT angiography (CCTA) across three populations with differing CAD prevalence, suggesting that CAA could be used in clinical practice, based on a study presented this week at the fifth annual meeting of the Society of Cardiovascular Computed Tomography (SCCT).
Thursday, July 15 2010
Written by Mary Stevens
OJAI, Calif.–The goal was to make meaningful use ambitious, but achievable, said Farzad Mostashari, senior advisor for policy and programming at the Office of the National Coordinator for Health IT (ONC), who clarified several points and answered many questions about meaningful use at the AMDIS Physician-Computer Connection Symposium Thursday.
Wednesday, July 14 2010
Written by Mary Stevens
OJAI, Calif. –CPOE implementation in any facility is challenging, but CMIOs from two pediatric hospitals said unintended consequences can be anticipated and mitigated or avoided altogether. At the AMDIS Physician-Computer Connection Symposium yesterday, James Levin, MD, PhD, CMIO of Children’s Hospital of Pittsburgh of the UPMC, and Christopher Longhurst, MD, CMIO of Lucile Packard Hospital in Stanford, Calif., talked about implementation and its results at their facilities.
Wednesday, July 14 2010
Written by Mary Stevens
OJAI, Calif.—A first look at the 864-page final rule for Meaningful Use and EHR Certification shows that policymakers “listened and responded” to some physicians’ concerns, said speakers Pat Wise, RN, vice president of healthcare information systems at HIMSS, and Michael Zaroukian, MD, PhD, CMIO and associate professor of medicine at Michigan State University, during a presentation at the annual AMDIS Physician-Computer Connection Symposium Wednesday.
Thursday, July 08 2010
For high risk Medicare Advantage patients with diabetes and coronary artery disease, use of a telephone-based disease management program has shown a decline in the number of inpatient hospital admissions and overall hospital costs, according to a study presented June 21 at the 92nd annual Endocrine Society meeting in San Diego.
Sunday, June 27 2010
Having diabetes approximately doubles the risk of developing a range of blood vessel disease states, including heart attacks and strokes, according to a study published June 24 in Lancet, and presented at the American Diabetes Association (ADA) conference in Orlando, Fla. Diabetes is estimated to be responsible for one in every 10 deaths from cardiovascular disease, or about 325,000 cardiovascular deaths annually in all industrialized countries combined.
Thursday, June 24 2010
Use of the once-weekly receptor agonist exenatide (Byetta, Amylin/Eli Lilly) showed better glucose control in diabetic patients who have suboptimal glucose control and where body weight and hypoglycemia were of concern, compared to a treatment with insulin glargine (Lantus, Sanofi Aventis) injection, according to DURATION-3 trial results presented at the annual American Diabetes Association (ADA) conference in Orlando, Fla., and simultaneously published in the June 24 edition of the Lancet.
Thursday, June 24 2010
Adding dapagliflozin to metformin as a treatment for type 2 diabetes patients who cannot reach adequate glucose control can improve glucose control and lower body weight without risk of hyperglycemia, according to trial results, presented at the annual conference of the American Diabetes Association (ADA) in Orlando, Fla., and published in the June 24 edition of the Lancet.
Tuesday, June 15 2010
The right ventricular (RV) basal diastolic dimension is an echocardiography parameter that can independently assess mortality in patients undergoing mitral valve surgery, according to a study presented this week at the 21st annual scientific sessions of the American Society of Echocardiography (ASE) meeting in San Diego.
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