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Subclinical leaflet thrombosis occurred in 13.6 percent of patients undergoing transcatheter aortic valve replacement (TAVR) and 3.8 percent of patients undergoing surgical aortic valve replacement (SAVR), according to an analysis of two registries.
A randomized study found that using two FDA-approved cerebral embolic protection devices in patients undergoing surgical aortic valve replacement (SAVR) was not associated with an improvement in freedom from clinical or radiographic infarction or clinical stroke.
At 12 months, patients with stable angina or acute coronary syndrome had similar rates of major adverse cardiac events whether they underwent revascularization guided by instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR), according to a randomized, registry-based trial.
Patients with chronic total occlusions (CTOs) had similar results whether they underwent PCIs or received optimal medical treatment, according to a prospective, open-label, randomized trial.
Patients with hypertension who received an electronic counseling intervention had a 10.1 mmHg reduction in systolic blood pressure after a year compared with a six mmHg reduction for a control group, according to a randomized, double-blind controlled trial in Canada.
An analysis of two randomized trials found that taking bococizumab had no benefits with regards to reducing the risk of major adverse cardiovascular events in lower cardiovascular risk patients.
After two years, intermediate-risk patients with severe symptomatic aortic stenosis had similar rates of all-cause mortality or disabling stroke whether they underwent transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR), according to a randomized trial.
Although patients with atherosclerotic cardiovascular disease and high levels of low-density lipoprotein (LDL) cholesterol benefited from receiving evolocumab plus statin therapy, the results of the randomized FOURIER trial did not impress Wall Street as shares of the drug’s manufacturer, Amgen, declined shortly after the findings were announced.